Disease-specific survival outcomes for patients after locoregional treatment for ductal carcinoma <i>in situ</i>: observational cohort study
There was no statistically significant difference in disease-specific survival between women operated with breast-conserving surgery alone, breast-conserving surgery with radiation treatment, or mastectomy for ductal carcinoma in situ. Given the low absolute risk of disease-specific mortality, these results provide confidence in offering individualized locoregional treatment without fear of compromising survival.
Authors
- Samantha Thomas (ORCID: https://orcid.org/0000-0001-6448-0830)
- Marc D. Ryser (ORCID: https://orcid.org/0000-0002-4990-0849)
- Lars J. Grimm (ORCID: https://orcid.org/0000-0002-3865-3352)
- Amanda L. Nash (ORCID: https://orcid.org/0000-0002-5558-212X)
- Elizabeth S. Frank (ORCID: https://orcid.org/0000-0001-9268-5104)
- Alastair Mark Thompson (ORCID: https://orcid.org/0000-0003-0604-7267)
- Amanda B. Francescatti (ORCID: https://orcid.org/0000-0002-3099-4726)
- Ann H. Partridge (ORCID: https://orcid.org/0000-0002-4722-4824)
- Terry Hyslop (ORCID: https://orcid.org/0000-0002-3930-8876)
- Sabrina M. Wang (ORCID: https://orcid.org/0000-0001-9225-585X)
- Thomas R. Lynch (ORCID: https://orcid.org/0000-0003-1270-6097)
- Esther Hwang (ORCID: https://orcid.org/0000-0002-6317-2518)
- Yan Li (ORCID: https://orcid.org/0000-0001-6574-1502)
- Yi Ren (ORCID: https://orcid.org/0000-0003-2218-9935)
- Anne Barber
Institutions
- Rush University Medical Center (US)
- Thomas Jefferson University (US)
- Duke University (US)
- Baylor College of Medicine (US)
- Sidney Kimmel Cancer Center (US)
- Dana-Farber Cancer Institute (US)
- Duke Medical Center (US)
- Duke University Hospital (US)
- American College of Surgeons (US)
Publication Details
- Journal
- British journal of surgery
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1093/bjs/znae198
- Citations
- 2
- Primary Topic
- Global Cancer Incidence and Screening
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Breast Cancer Research Foundation
- Patient-Centered Outcomes Research Institute
- Cancer Research UK
- Pancreatic Cancer Action
- National Institutes of Health