Clinical Impact of Pleural Fluid <i>Streptococcus pneumoniae</i> Polymerase Chain Reaction Testing in Children With Complicated Pneumonia
Spn molecular testing of pleural fluid in children with cCAP resulted in significantly more microbiologic diagnoses and was associated with the optimization of antibiotics and decreased exposure to MRSA therapy, suggesting its clinical impact for pediatric complicated pneumonia.
Authors
- Kristen Miller (ORCID: https://orcid.org/0000-0002-8991-2342)
- Sarah Jung (ORCID: https://orcid.org/0000-0002-7414-9276)
- Samuel R. Dominguez (ORCID: https://orcid.org/0000-0002-6707-5088)
- Edwin J. Asturias (ORCID: https://orcid.org/0000-0002-1275-0787)
- Erin C Ho (ORCID: https://orcid.org/0000-0002-7425-5466)
- Meghan Birkholz
- Kevin Messacar (ORCID: https://orcid.org/0000-0001-5830-3491)
- Molly Butler (ORCID: https://orcid.org/0009-0006-3820-4377)
- Christine E. MacBrayne (ORCID: https://orcid.org/0009-0005-8410-197X)
- Kaitlin E Olson
Institutions
- Children's Hospital Colorado (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1093/cid/ciae439
- Citations
- 13
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 5.03
Funders
- Pfizer
- Sanofi
- Pediatric Infectious Diseases Society
- BioFire Diagnostics
- Sanofi Pasteur