Synthesis of 2‐Amino Benzazoles Through Elemental Selenium‐Promoted Cyclization of <i>Ortho</i>‐Substituted Anilines and Isocyanides
Abstract A facile and transition metal‐free method has been developed for the synthesis of 2‐amino benzazoles through elemental selenium promoted cyclization reaction of ortho ‐substituted anilines with isocyanides under mild conditions. Through this strategy, a series of 2‐amino benzooxa/(thia)zoles and benzimidazoles could be efficiently obtained in good to excellent yields with favorable functional group tolerance.
Authors
- Jinmao You (ORCID: https://orcid.org/0000-0002-8808-6085)
- Siyu Shi (ORCID: https://orcid.org/0000-0001-9010-7431)
- Dong Yi (ORCID: https://orcid.org/0000-0002-8281-7860)
- Wei Wei (ORCID: https://orcid.org/0000-0002-0015-7636)
- Chao Ma
- Yufen Lv (ORCID: https://orcid.org/0009-0003-9634-304X)
- Hongyu Ding
- Wenxiu Cui
Institutions
- Shaoxing University (CN)
- Qufu Normal University (CN)
- Southwest Medical University (CN)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1002/ejoc.202400903
- Citations
- 1
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province