Opioid receptors: single molecule studies shed light on mechanisms of efficacy

Research Highlight: In a study recently published in Nature, Zhao et al.1 investigate the conformational dynamics of the µ-opioid receptor (µOR). They found evidence for previously unknown conformations of this receptor which could eventually improve the therapy of severe pain.

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Publication Details

Journal
Signal Transduction and Targeted Therapy
Published
2024-08-30
DOI
https://doi.org/10.1038/s41392-024-01920-2
Primary Topic
Receptor Mechanisms and Signaling
Type
article
Field-Weighted Citation Impact
0.00
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article

Opioid receptors: single molecule studies shed light on mechanisms of efficacy

Cornelius Krasel, Moritz Bünemann
Signal Transduction and Targeted Therapy
Receptor Mechanisms and Signaling
article

Opioid receptors: single molecule studies shed light on mechanisms of efficacy

Cornelius Krasel, Moritz Bünemann
article en

Abstract

Research Highlight: In a study recently published in Nature, Zhao et al.1 investigate the conformational dynamics of the µ-opioid receptor (µOR). They found evidence for previously unknown conformations of this receptor which could eventually improve the therapy of severe pain.

Signal Transduction and Targeted TherapyVol. 9(1)
Philipps University of Marburg (DE)
Zero hunger
Openalex Percentile: Top 87%
Receptor Mechanisms and Signaling
DOIOpen Access PDFOpenAlex
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Opioid receptors: single molecule studies shed light on mechanisms of efficacy — Cornelius Krasel, Moritz Bünemann · Signal Transduction and Targeted Therapy (2024) | TGRS Research Map | TGRS