Text summarization for pharmaceutical sciences using hierarchical clustering with a weighted evaluation methodology

In the pharmaceutical industry, there is an abundance of regulatory documents used to understand the current regulatory landscape and proactively make project decisions. Due to the size of these documents, it is helpful for project teams to have informative summaries. We propose a novel solution, MedicoVerse, to summarize such documents using advanced machine learning techniques. MedicoVerse uses a multi-stage approach, combining word embeddings using the SapBERT model on regulatory documents. These embeddings are put through a critical hierarchical agglomerative clustering step, and the clusters are organized through a custom data structure. Each cluster is summarized using the bart-large-cnn-samsum model, and each summary is merged to create a comprehensive summary of the original document. We compare MedicoVerse results with established models T5, Google Pegasus, Facebook BART, and large language models such as Mixtral 8 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mo>×</mml:mo></mml:math> 7b instruct, GPT 3.5, and Llama-2-70b by introducing a scoring system that considers four factors: ROUGE score, BERTScore, business entities and the Flesch Reading Ease. Our results show that MedicoVerse outperforms the compared models, thus producing informative summaries of large regulatory documents.

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Publication Details

Journal
Scientific Reports
Published
2024-08-30
DOI
https://doi.org/10.1038/s41598-024-70618-w
Citations
9
Primary Topic
Topic Modeling
Type
article
Field-Weighted Citation Impact
3.13

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article

Text summarization for pharmaceutical sciences using hierarchical clustering with a weighted evaluation methodology

Sumit Ranjan, C. Sean Burns, N. Steiger, Yajna Bopaiah et al.
9 citations
Scientific Reports
Topic Modeling
3.13
article

Text summarization for pharmaceutical sciences using hierarchical clustering with a weighted evaluation methodology

Sumit Ranjan, C. Sean Burns, N. Steiger, Yajna Bopaiah, Divya Chembachere, Varsha Daswani, Avinash Dalal
article en
9 citations

Abstract

In the pharmaceutical industry, there is an abundance of regulatory documents used to understand the current regulatory landscape and proactively make project decisions. Due to the size of these documents, it is helpful for project teams to have informative summaries. We propose a novel solution, MedicoVerse, to summarize such documents using advanced machine learning techniques. MedicoVerse uses a multi-stage approach, combining word embeddings using the SapBERT model on regulatory documents. These embeddings are put through a critical hierarchical agglomerative clustering step, and the clusters are organized through a custom data structure. Each cluster is summarized using the bart-large-cnn-samsum model, and each summary is merged to create a comprehensive summary of the original document. We compare MedicoVerse results with established models T5, Google Pegasus, Facebook BART, and large language models such as Mixtral 8 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mo>×</mml:mo></mml:math> 7b instruct, GPT 3.5, and Llama-2-70b by introducing a scoring system that considers four factors: ROUGE score, BERTScore, business entities and the Flesch Reading Ease. Our results show that MedicoVerse outperforms the compared models, thus producing informative summaries of large regulatory documents.

Scientific ReportsVol. 14(1)
Pfizer (United States) (US), Theodore Roosevelt High School (US), Decision Sciences (United States) (US), Doylestown Hospital (US), Applied Sciences (United States) (US), Dassault Systèmes (France) (FR), Incyte (United States) (US)
Pfizer
Openalex Percentile: Top 7%
Topic Modeling
3.13
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Text summarization for pharmaceutical sciences using hierarchical clustering with a weighted evaluation methodology — Sumit Ranjan, C. Sean Burns, et al. · Scientific Reports (2024) | TGRS Research Map | TGRS