Co-delivery of camptothecin and MiR-145 by lipid nanoparticles for MRI-visible targeted therapy of hepatocellular carcinoma
The LA-CMGL-mediated co-delivery of miR-145 and CPT displays a synergistic therapy against HCC. The novel MRI-visible, actively targeted chemo-gene co-delivery system for HCC therapy provides a scientific basis and a useful idea for the development of HCC treatment strategies in the future.
Authors
- Min Shao (ORCID: https://orcid.org/0000-0002-6922-0445)
- Qi Liu (ORCID: https://orcid.org/0000-0002-3285-7864)
- Saisai Zhang (ORCID: https://orcid.org/0000-0002-0603-8873)
- Xiujuan Yin
- Lei Zhang (ORCID: https://orcid.org/0000-0003-3638-6219)
- Tongtong Liu (ORCID: https://orcid.org/0009-0004-3694-5011)
- Kun Zhu (ORCID: https://orcid.org/0000-0002-9664-6927)
- Yujie Zhu
- Likang Yin
- Jing Rong
- Shiqi Wang
- Bin Li
- Xiao Wang (ORCID: https://orcid.org/0000-0003-1955-3687)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1186/s13046-024-03167-9
- Citations
- 31
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 7.25
Funders
- National Natural Science Foundation of China
- Anhui Medical University