Neurological activation during verbal fluency task and resting-state functional connectivity abnormalities in obsessive-compulsive disorder: a functional near-infrared spectroscopy study
The study highlights significant disparities in neural activation and functional connectivity between OCD patients and healthy controls during VFT. Specifically, reduced activation was noted in the frontal and bilateral temporal lobes of OCD patients, alongside alterations in resting-state functional connectivity between the IFG and DLPFC. These findings contribute to our understanding of the neurobiological underpinnings of OCD and may guide future therapeutic strategies.
Authors
- Chuanxin M. Niu (ORCID: https://orcid.org/0000-0001-6013-2492)
- Xiaohui Song (ORCID: https://orcid.org/0000-0002-6723-3023)
- Yan Jin (ORCID: https://orcid.org/0000-0002-6502-5837)
- Qing Xie (ORCID: https://orcid.org/0000-0003-2889-5670)
- Yongjun Qiao
- Wenxiu Pan
- Chin-Hsuan Chia (ORCID: https://orcid.org/0000-0002-3343-9541)
- Haiyan Jin (ORCID: https://orcid.org/0000-0003-4070-1365)
- Dan Zhao
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3389/fpsyt.2024.1416810
- Citations
- 10
- Primary Topic
- Obsessive-Compulsive Spectrum Disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.39
Funders
- National Natural Science Foundation of China
- Shanghai Jiao Tong University
- Ruijin Hospital
- School of Medicine, Shanghai Jiao Tong University