Identification of immune-related endoplasmic reticulum stress genes in proliferative diabetic retinopathy using bioinformatics analysis
This study provides a comprehensive molecular characterization of ER stress in PDR, highlighting altered biological processes, immune changes, and potential therapeutic targets. The identified hub genes and small molecules offer avenues for further investigation and therapy development, enhancing understanding of PDR pathogenesis and aiding targeted intervention creation.
Authors
- Han Chen (ORCID: https://orcid.org/0000-0002-9510-4923)
- Enguang Chen (ORCID: https://orcid.org/0000-0002-8031-5234)
- Jianhui Wang (ORCID: https://orcid.org/0000-0002-6261-4863)
- Jiawei Yin
- Peiquan Zhao (ORCID: https://orcid.org/0000-0001-6956-9359)
- Miaomiao Liu (ORCID: https://orcid.org/0009-0005-2834-7799)
- Yu Xu (ORCID: https://orcid.org/0000-0002-7363-742X)
Institutions
- Shanghai Jiao Tong University (CN)
- XinHua Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3389/fendo.2024.1341206
- Citations
- 4
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.30
Funders
- Science and Technology Commission of Shanghai Municipality