Identification of immune-related biomarkers for intracerebral hemorrhage diagnosis based on RNA sequencing and machine learning
This study demonstrated that the expression levels of lncRNAs and mRNAs are associated with ICH, and an RNA panel (CKAP4, BCL6, TLR8) was developed as a potential diagnostic tool for distinguishing ICH from IS and controls, which could provide useful insight into ICH diagnosis and pathogenesis.
Authors
- Fengjuan Wang (ORCID: https://orcid.org/0009-0001-6751-8854)
- Congxia Bai (ORCID: https://orcid.org/0000-0001-9851-8470)
- Yingying Sun (ORCID: https://orcid.org/0000-0003-2633-5784)
- Xinran Liu (ORCID: https://orcid.org/0000-0002-0650-9022)
- Xiaoyan Hao (ORCID: https://orcid.org/0000-0002-4370-8821)
- Yu Yuan
- Lei Zhou (ORCID: https://orcid.org/0009-0008-3550-3528)
- Jing Liu (ORCID: https://orcid.org/0009-0007-3796-7046)
- Jing Wang (ORCID: https://orcid.org/0000-0001-7431-8925)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Affiliated Hospital of Hebei University (CN)
- Xijing Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3389/fimmu.2024.1421942
- Citations
- 10
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 3.69
Funders
- National Natural Science Foundation of China