The shared molecular mechanism of spinal cord injury and sarcopenia: a comprehensive genomics analysis
Our study provides comprehensive insights into how muscle changes after SCI are associated with sarcopenia by moving from RNA-seq to RNA-SEQ, including Immune infiltration landscape, pesudotime change and so on. The three hub genes identified in this study could be used to distinguish the sarcopenia state at the genomic level. Additionally, they may also play a prognostic role in evaluating the efficiency of rehabilitation training.
Authors
- Chuanxiong Li (ORCID: https://orcid.org/0000-0002-7511-9933)
- Xu Yang (ORCID: https://orcid.org/0009-0000-4378-6232)
- B H Wang (ORCID: https://orcid.org/0000-0003-4501-7685)
- Yong Yin
- Tong Sun (ORCID: https://orcid.org/0000-0003-3861-8933)
- Rongxing Yang
Institutions
- Yunnan University (CN)
- Kunming Medical University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3389/fneur.2024.1373605
- Citations
- 1
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.44