Green Synthesis of Silver (Ag) Nanoparticles with Green Tea Leaf, Its Characterization, and Molecular Docking Analysis against Diabetes

The Green synthesis method is proved to be one of the simplest and efficient ways for material synthesis. Silver nanoparticles were synthesized using a green synthesis method, with silver nitrate and green tea leaves as precursors. The sample is then characterized using versatile characterization techniques such as Scanning Electron Microscope (SEM), UV Spectroscopy, Raman Spectroscopy and Particle size analyser (PSA). The PSA pattern has shown that the particles are pure. The surface morphology is obtained through SEM image and it has suggested that nano particles were aggregates. The nanoparticles have shown interactions between silver and oxygen atoms supported by Raman. Molecular docking is a pivotal computational technique widely used in drug discovery to predict the preferred orientation of a ligand as it binds to a receptor's active site. This approach is fundamental to understand molecular interactions at the atomic level, thereby facilitating the design of new drugs by high affinity and specificity. The process involves simulating the interaction between molecules to determine the optimal binding configuration, using algorithms that assess the binding energy and stability of the resulting complex.