Mediation effect of stroke recurrence in the association between post-stroke lactate dehydrogenase and functional disability
The relationship between LDH and functional disability at 90 days among AIS patients is partially mediated by stroke recurrence, accounting for less than 20%. LDH deserves equal attention as hs-CRP in predicting recurrence and functional outcome. In addition to traditional secondary prevention measures, innovative anti-inflammatory strategies warrant further investigation.
Authors
- Wen Rui (ORCID: https://orcid.org/0000-0002-1616-0469)
- Miaoran Wang (ORCID: https://orcid.org/0000-0002-7561-7086)
- Linzhi Zhang (ORCID: https://orcid.org/0000-0002-3311-3584)
- Qian He (ORCID: https://orcid.org/0000-0002-5686-9835)
- Ying Xiao (ORCID: https://orcid.org/0000-0001-8558-6394)
- Xiaoqing Liu (ORCID: https://orcid.org/0000-0001-8162-0903)
- Bing Xu (ORCID: https://orcid.org/0009-0007-1083-4171)
- Yangdi Shi
- Yu Wang (ORCID: https://orcid.org/0000-0001-8697-2940)
- Haoyue Zhu
Institutions
- Shenyang First People's Hospital (CN)
- China Medical University (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3389/fnagi.2024.1450863
- Citations
- 3
- Primary Topic
- Stroke Rehabilitation and Recovery
- Type
- article
- Field-Weighted Citation Impact
- 0.75