A real-world disproportionality analysis of FDA adverse event reporting system (FAERS) events for denosumab
These findings underscore the critical importance of pharmacovigilance and are consistent with established clinical observations. Notably, osteonecrosis of the jaw, arthralgia, pain in extremities, back pain, myalgia, and bone pain were identified as the most prevalent risk signals associated with denosumab.
Authors
- Huarui Shen (ORCID: https://orcid.org/0009-0004-8038-4215)
- Yingqi Liu (ORCID: https://orcid.org/0000-0002-3934-0673)
- Yue He (ORCID: https://orcid.org/0000-0003-4041-9271)
- Rong Zhang (ORCID: https://orcid.org/0000-0003-3793-6550)
Institutions
- Southwest University (CN)
- Southwest Medical University (CN)
- Southwest Hospital (CN)
- Sichuan Provincial Hospital of Traditional Chinese Medicine (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3389/fphar.2024.1339721
- Citations
- 9
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.54
Funders
- Natural Science Foundation of Chongqing
- Centre Scientifique et Technique du Bâtiment
- Sichuan Provincial Administration of Traditional Chinese Medicine
- Sichuan Province Science and Technology Support Program