Idiopathic multicentric Castleman disease with marrow fibrosis and extramedullary hematopoiesis
This case series demonstrates that EMH can be seen in CD, particularly in iMCD-TAFRO. Given the similarity of this finding to previous murine models of IL-6-induced marrow and lymph node changes we hypothesize that this is an IL-6-mediated phenomenon.
Authors
- Emilie Comeau (ORCID: https://orcid.org/0000-0002-6713-5378)
- Marley Blommers
- David C. Fajgenbaum (ORCID: https://orcid.org/0000-0002-7367-8184)
- Elizabeth Wiley
- Allam Shawwa
- Saishravan Shyamsundar (ORCID: https://orcid.org/0000-0002-0160-8910)
- Mateo Sarmiento Bustamante (ORCID: https://orcid.org/0009-0002-6774-2714)
- Luke Y. C. Chen (ORCID: https://orcid.org/0000-0002-9551-2951)
- Sorin Selegean
- Richard K. Wood (ORCID: https://orcid.org/0000-0002-3976-6420)
- Stefan Rose‐John (ORCID: https://orcid.org/0000-0002-7519-3279)
Institutions
- Dalhousie University (CA)
- University of British Columbia (CA)
- Christian-Albrechts-Universität zu Kiel (DE)
- University of Pennsylvania (US)
Publication Details
- Journal
- European Journal Of Haematology
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1111/ejh.14295
- Citations
- 3
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Clinton Foundation
- Recordati Rare Diseases
- National Heart, Lung, and Blood Institute