Dock4 contributes to neuropathic pain by regulating spinal synaptic plasticity in mice
In summary, our data indicated that Dock4 facilitated excitatory synaptic transmission by promoting the expression of GluN2B at the synaptic site and synaptogenesis, leading to the occurrence of NP.
Authors
- Qiaochu Fu (ORCID: https://orcid.org/0000-0002-3001-0061)
- Wencui Li
- Ruijie Chang
- Huixia Wei (ORCID: https://orcid.org/0000-0002-4901-3967)
- Zhihua Ruan (ORCID: https://orcid.org/0000-0002-8757-4175)
- Hongyi Li (ORCID: https://orcid.org/0000-0002-7590-7411)
- Yanqiong Wu
- Xueqin Xu (ORCID: https://orcid.org/0000-0002-1657-6253)
- Zhuanxu Zhu
- Xunliang Xu
Institutions
- Hubei University of Medicine (CN)
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Tian Tan Hospital (CN)
- Taihe Hospital (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Molecular Neuroscience
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3389/fnmol.2024.1417567
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00