Anatomical classification of advanced biliary tract cancer predicts programmed cell death protein 1 blockade efficacy
This study shows that the efficacy of anti-PD1 therapy was higher in ICC than in other types of BTCs. Differences in the immune-related molecules and cells between ICC and ECC indicate that ICC could benefit more from immunotherapy.
Authors
- Jinsheng Huang (ORCID: https://orcid.org/0000-0002-6371-4532)
- Xujia Li (ORCID: https://orcid.org/0009-0007-5506-2320)
- Lingli Huang (ORCID: https://orcid.org/0000-0003-2991-8838)
- Fang Wang (ORCID: https://orcid.org/0009-0009-7713-561X)
- Fenghua Wang (ORCID: https://orcid.org/0000-0001-9670-1036)
- Qi Jiang (ORCID: https://orcid.org/0000-0002-9380-1864)
- Guifang Guo (ORCID: https://orcid.org/0000-0003-1197-1147)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3389/fphar.2024.1375769
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Guangdong Province