A rare association of cervical tuberculosis and primary infertility in a young nulligravida female

Tuberculosis of the cervix is rare and may have a clinical presentation and hypertrophic growth like morphological appearance masquerading as that of cervical carcinoma. Due to nonspecific symptoms, there is often a delay in diagnosis and treatment, and thereby increasing the risk of infertility in young females. Here, we present a rare case of a 26 years young female with primary infertility and cervical tuberculosis. The patient presented with complaints of being keen to conceive for 3 years and occasional post coital spotting p/v. Her ultrasonography (USG) pelvis and hormonal analysis and her husband’s semen analysis reports were normal. On per-speculum examination, the ectocervix was replaced by a friable growth that bled on touch. A biopsy of the growth was taken and sent for tuberculosis (TB), cartridge based nucleic acid amplification test (CBNAAT), and histopathology. Her CBNAAT was negative, but her histopathology showed numerous epithelioid cell granulomas along with Langhans giant cells and scant central necrosis, suggestive of tuberculosis of the cervix. The patient was sent to a TB clinic and was prescribed anti-tubercular therapy for 6 months. Thus, in any case of infertility in a young female with cervical growth mimicking cervical carcinoma, a differential diagnosis should always be kept in mind.

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Publication Details

Journal
International Journal of Reproduction Contraception Obstetrics and Gynecology
Published
2024-08-29
DOI
https://doi.org/10.18203/2320-1770.ijrcog20242515
Citations
1
Primary Topic
Diagnosis and treatment of tuberculosis
Type
article
Field-Weighted Citation Impact
0.57
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article

A rare association of cervical tuberculosis and primary infertility in a young nulligravida female

Kripa Yadav, Susmita Sah, Ravi Sah, Garvita Gulati et al.
1 citations
International Journal of Reproduction Contraception Obstetrics and Gynecology
Diagnosis and treatment of tuberculosis
0.57
article

A rare association of cervical tuberculosis and primary infertility in a young nulligravida female

Kripa Yadav, Susmita Sah, Ravi Sah, Garvita Gulati, Akansha Deshwali, Parish Kamdi, Vanshika Asati, Manisha Perka, Shriya Rawat, D V S Reddy, Shalini Bose
article en
1 citations

Abstract

Tuberculosis of the cervix is rare and may have a clinical presentation and hypertrophic growth like morphological appearance masquerading as that of cervical carcinoma. Due to nonspecific symptoms, there is often a delay in diagnosis and treatment, and thereby increasing the risk of infertility in young females. Here, we present a rare case of a 26 years young female with primary infertility and cervical tuberculosis. The patient presented with complaints of being keen to conceive for 3 years and occasional post coital spotting p/v. Her ultrasonography (USG) pelvis and hormonal analysis and her husband’s semen analysis reports were normal. On per-speculum examination, the ectocervix was replaced by a friable growth that bled on touch. A biopsy of the growth was taken and sent for tuberculosis (TB), cartridge based nucleic acid amplification test (CBNAAT), and histopathology. Her CBNAAT was negative, but her histopathology showed numerous epithelioid cell granulomas along with Langhans giant cells and scant central necrosis, suggestive of tuberculosis of the cervix. The patient was sent to a TB clinic and was prescribed anti-tubercular therapy for 6 months. Thus, in any case of infertility in a young female with cervical growth mimicking cervical carcinoma, a differential diagnosis should always be kept in mind.

International Journal of Reproduction Contraception Obstetrics and GynecologyVol. 13(9)
All India Institute of Medical Sciences Rishikesh (IN), All India Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 30%
Diagnosis and treatment of tuberculosis
0.57
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