Analysis of Depression and Anxiety Scores Following Initiation of Elexacaftor/Tezacaftor/Ivacaftor in Adults With Cystic Fibrosis

Treatment with E/T/I does not lead to changes in depression or anxiety symptoms at the population level in this single center cohort study. A prior diagnosis of depression trended towards an increased odds of worsening PHQ-9 scores after E/T/I initiation.

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Publication Details

Journal
The Clinical Respiratory Journal
Published
2024-08-29
DOI
https://doi.org/10.1111/crj.70007
Citations
9
Primary Topic
Cystic Fibrosis Research Advances
Type
article
Field-Weighted Citation Impact
3.77

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article

Analysis of Depression and Anxiety Scores Following Initiation of Elexacaftor/Tezacaftor/Ivacaftor in Adults With Cystic Fibrosis

Scott H. Donaldson, Margret Z. Powell, Jennifer L. Goralski, Agathe Ceppe et al.
9 citations
The Clinical Respiratory Journal
Cystic Fibrosis Research Advances
3.77
article

Analysis of Depression and Anxiety Scores Following Initiation of Elexacaftor/Tezacaftor/Ivacaftor in Adults With Cystic Fibrosis

Scott H. Donaldson, Margret Z. Powell, Jennifer L. Goralski, Agathe Ceppe, Nathaniel A. Sowa, Harish Pudukodu
article en
9 citations

Abstract

Treatment with E/T/I does not lead to changes in depression or anxiety symptoms at the population level in this single center cohort study. A prior diagnosis of depression trended towards an increased odds of worsening PHQ-9 scores after E/T/I initiation.

The Clinical Respiratory JournalVol. 18(9)
University of North Carolina at Chapel Hill (US), Brigham and Women's Hospital (US), Baylor University (US)
National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, School of Medicine, University of North Carolina at Chapel Hill
Good health and well-being
Openalex Percentile: Top 6%
Cystic Fibrosis Research Advances
3.77
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