Efficacy and safety of intravenous ketamine treatment in Japanese patients with treatment‐resistant depression: A double‐blind, randomized, placebo‐controlled trial
Intravenous ketamine outperformed placebo in Japanese patients with TRD who completed the study, suggesting that ketamine could alleviate depressive symptoms of TRD across diverse ethnic populations.
Authors
- Takuya Takahashi (ORCID: https://orcid.org/0000-0001-6523-0622)
- Kengo Yonezawa
- Sadamitsu Ichijo (ORCID: https://orcid.org/0000-0001-8135-5740)
- Hiroyuki Uchida (ORCID: https://orcid.org/0000-0002-0628-7036)
- Yu Fujimoto (ORCID: https://orcid.org/0000-0001-8475-0535)
- Sakiko Tsugawa (ORCID: https://orcid.org/0000-0001-9974-316X)
- Tomoyuki Miyazaki (ORCID: https://orcid.org/0000-0003-3840-5436)
- Nobuhiro Nagai (ORCID: https://orcid.org/0000-0003-2826-4959)
- Keisuke Kusudo
- Takashige Yamada (ORCID: https://orcid.org/0000-0002-1152-9853)
- Shinichiro Nakajima (ORCID: https://orcid.org/0000-0002-2601-2195)
- Taisuke Yatomi
- Hideaki Tani (ORCID: https://orcid.org/0000-0002-8782-0399)
- Sotaro Moriyama
- Yohei Ohtani (ORCID: https://orcid.org/0009-0007-1313-0049)
- Shiori Honda (ORCID: https://orcid.org/0000-0002-3756-0584)
- Hiroshi Morisaki (ORCID: https://orcid.org/0000-0002-2790-2093)
- Yu Iwabuchi (ORCID: https://orcid.org/0000-0002-9259-6651)
- Tsuyoshi Eiro
- Kie Nomoto‐Takahashi
- Kimio Yoshimura
- Sota Tomiyama
- Masahiro Jinzaki
Institutions
- Keio University (JP)
- Zero to Three (US)
- Sapporo Minami Hospital (JP)
- Yokohama City University (JP)
Publication Details
- Journal
- Psychiatry and Clinical Neurosciences
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1111/pcn.13734
- Citations
- 9
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Takeda Science Foundation
- Japan Research Foundation for Clinical Pharmacology
- Japan Agency for Medical Research and Development
- Boehringer Ingelheim Japan
- Keio University
- Dainippon Sumitomo Pharma
- Eisai
- Meiji Seika Pharma
- Shionogi
- Otsuka Pharmaceutical
- SENSHIN Medical Research Foundation
- Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering
- H. Lundbeck A/S
- Japan Society for the Promotion of Science
- Japan Science and Technology Agency
- Daiichi Sankyo Europe