Efficacy and safety of intravenous ketamine treatment in Japanese patients with treatment‐resistant depression: A double‐blind, randomized, placebo‐controlled trial

Intravenous ketamine outperformed placebo in Japanese patients with TRD who completed the study, suggesting that ketamine could alleviate depressive symptoms of TRD across diverse ethnic populations.

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Publication Details

Journal
Psychiatry and Clinical Neurosciences
Published
2024-08-30
DOI
https://doi.org/10.1111/pcn.13734
Citations
9
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
4.03

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article

Efficacy and safety of intravenous ketamine treatment in Japanese patients with treatment‐resistant depression: A double‐blind, randomized, placebo‐controlled trial

Takuya Takahashi, Kengo Yonezawa, Sadamitsu Ichijo, Hiroyuki Uchida et al.
9 citations
Psychiatry and Clinical Neurosciences
Treatment of Major Depression
4.03
article

Efficacy and safety of intravenous ketamine treatment in Japanese patients with treatment‐resistant depression: A double‐blind, randomized, placebo‐controlled trial

Takuya Takahashi, Kengo Yonezawa, Sadamitsu Ichijo, Hiroyuki Uchida, Yu Fujimoto, Sakiko Tsugawa, Tomoyuki Miyazaki, Nobuhiro Nagai, Keisuke Kusudo, Takashige Yamada, Shinichiro Nakajima, Taisuke Yatomi, Hideaki Tani, Sotaro Moriyama, Yohei Ohtani, Shiori Honda, Hiroshi Morisaki, Yu Iwabuchi, Tsuyoshi Eiro, Kie Nomoto‐Takahashi, Kimio Yoshimura, Sota Tomiyama, Masahiro Jinzaki
article en
9 citations

Abstract

Intravenous ketamine outperformed placebo in Japanese patients with TRD who completed the study, suggesting that ketamine could alleviate depressive symptoms of TRD across diverse ethnic populations.

Psychiatry and Clinical NeurosciencesVol. 78(12)
Keio University (JP), Zero to Three (US), Sapporo Minami Hospital (JP), Yokohama City University (JP)
Takeda Science Foundation, Japan Research Foundation for Clinical Pharmacology, Japan Agency for Medical Research and Development, Boehringer Ingelheim Japan, Keio University, Dainippon Sumitomo Pharma, Eisai, Meiji Seika Pharma, Shionogi, Otsuka Pharmaceutical, SENSHIN Medical Research Foundation, Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering, H. Lundbeck A/S, Japan Society for the Promotion of Science, Japan Science and Technology Agency, Daiichi Sankyo Europe
Good health and well-being
Openalex Percentile: Top 6%
Treatment of Major Depression
4.03
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