Utility of placental biomarkers and fetoplacental Dopplers in predicting likely placental pathology in early and late fetal growth restriction – A prospective study
MVM was the commonest placental abnormality in FGR, particularly in early-onset disease. Low maternal PlGF levels, high sFlt-1 levels, elevated sFlt-1/PlGF ratio, and abnormal fetoplacental Dopplers were also significantly associated with MVM. MVM, FVM, and CHI abnormalities were associated with lower median birthweight, higher rates of preterm birth, operative birth for non-reassuring fetal status, and severe neonatal non-neurological morbidity.
Authors
- Fabrício da Silva Costa (ORCID: https://orcid.org/0000-0002-0765-7780)
- Sailesh I.S. Kumar (ORCID: https://orcid.org/0000-0003-0832-4811)
- Rohan Lourie (ORCID: https://orcid.org/0000-0002-0093-911X)
- Kylie Crawford (ORCID: https://orcid.org/0000-0002-9403-0096)
- Anthony V. Perkins (ORCID: https://orcid.org/0000-0002-9829-6772)
- Jesrine Hong (ORCID: https://orcid.org/0000-0001-8585-2357)
- Admire Matsika (ORCID: https://orcid.org/0000-0002-4418-7394)
- Vicki Lee Clifton (ORCID: https://orcid.org/0000-0002-4892-6748)
- M. E. Daly
Institutions
- Griffith University (AU)
- The University of Queensland (AU)
- University of the Sunshine Coast (AU)
- Gold Coast Hospital (AU)
- Mater Research (AU)
Publication Details
- Journal
- Placenta
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1016/j.placenta.2024.08.016
- Citations
- 5
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 2.91