Factors associated with cause-specific discontinuation of long-term anti-tumor necrosis factor agent use in patients with ankylosing spondylitis: a retrospective cohort study
AS patients on their first anti-TNF treatment for at least two years demonstrated a favorable long-term treatment retention rate, with a 24.0% discontinuation rate over a 10.6-year overall survival period. The predictors for discontinuation varied by causes, underscoring the complexity of treatment response and the importance of personalized approaches to treatment management.
Authors
- Bora Nam (ORCID: https://orcid.org/0000-0003-0215-3855)
- Nayeon Choi (ORCID: https://orcid.org/0000-0002-0962-0594)
- Bon San Koo (ORCID: https://orcid.org/0000-0002-4212-2634)
- Jiyeong Kim (ORCID: https://orcid.org/0000-0001-7732-1521)
- Tae-Hwan Kim (ORCID: https://orcid.org/0000-0002-6432-1378)
Institutions
- Inje University Ilsan Paik Hospital (KR)
- Hanyang University Seoul Hospital (KR)
- Biostatistical Consulting (United States) (US)
- Hanyang University (KR)
- Anyang University (KR)
Publication Details
- Journal
- BMC Rheumatology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1186/s41927-024-00410-w
- Citations
- 1
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.47