Evaluation of SK-N-SH Cells as a Model for NMDA Receptor Induced Toxicity
SK-N-SH cells show an increased sensitivity to (<i>S</i>)-glutamate mediated cytotoxicity with higher differentiation level, that is only partially induced by NMDA receptor overstimulation. Furthermore, we showed that only unselective NMDA receptor inhibition can partially reverse (<i>S</i>)-glutamate-induced toxicity.
Authors
- Gunnar Goerges (ORCID: https://orcid.org/0000-0002-3952-320X)
- Julian A. Schreiber (ORCID: https://orcid.org/0000-0002-3847-7539)
Institutions
- University of Münster (DE)
- University Hospital Münster (DE)
Publication Details
- Journal
- Cellular Physiology and Biochemistry
- Published
- 2024-08-30
- DOI
- https://doi.org/10.33594/000000722
- Citations
- 2
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.54