Benign Granular Cell Tumor of Interarytenoid Fold: A Case Report and Comprehensive Review in South Korea

Granular cell tumor (GCT) is a extremely rare soft tissue tumor which can mimic the histopathology of squamous cell carcinoma (SCC). The character of GCT in larynx is usually benign but malignant change could be possible. Thus, it is important to distinguish laryngeal GCT from benign disease such as granuloma, polyp, not to mention malignant disease such as laryngeal SCC. The diagnosis is done by immunohistochemistry. Treatment for GCT is surgical removal with negative margin. Although systemic review of laryngeal GCT exists abroad, our literature made the first attempt to organize 13 cases in South Korea reported since 2002. We also present our case of patient with young age but with heavy smoking history in 2023 thereby contributing to cases of GCT of larynx reported in South Korea with possible correlation with smoking.

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Journal
Journal of The Korean Society of Laryngology Phoniatrics and Logopedics
Published
2024-08-30
DOI
https://doi.org/10.22469/jkslp.2024.35.2.70
Primary Topic
Tumors and Oncological Cases
Type
article
Field-Weighted Citation Impact
0.00

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article

Benign Granular Cell Tumor of Interarytenoid Fold: A Case Report and Comprehensive Review in South Korea

Seung Hoon Woo, Min Seok Moon
Journal of The Korean Society of Laryngology Phoniatrics and Logopedics
Tumors and Oncological Cases
article

Benign Granular Cell Tumor of Interarytenoid Fold: A Case Report and Comprehensive Review in South Korea

Seung Hoon Woo, Min Seok Moon
article en

Abstract

Granular cell tumor (GCT) is a extremely rare soft tissue tumor which can mimic the histopathology of squamous cell carcinoma (SCC). The character of GCT in larynx is usually benign but malignant change could be possible. Thus, it is important to distinguish laryngeal GCT from benign disease such as granuloma, polyp, not to mention malignant disease such as laryngeal SCC. The diagnosis is done by immunohistochemistry. Treatment for GCT is surgical removal with negative margin. Although systemic review of laryngeal GCT exists abroad, our literature made the first attempt to organize 13 cases in South Korea reported since 2002. We also present our case of patient with young age but with heavy smoking history in 2023 thereby contributing to cases of GCT of larynx reported in South Korea with possible correlation with smoking.

Journal of The Korean Society of Laryngology Phoniatrics and LogopedicsVol. 35(2)
Dankook University (KR)
Seoul National University Hospital
Good health and well-being
Openalex Percentile: Top 77%
Tumors and Oncological Cases
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