Vascular density normative data of radial peripapillary capillary plexus in healthy Caucasian subjects
What is known Radial peripapillary capillary (RPC) plexus, consisting of long parallel capillaries with rare bifurcations and anastomosis and extending straight along the course of the retinal nerve fiber layer to the posterior pole, may be affected early in some optic nerve head (ONH) and retinal diseases. What is new This study reports RPC vascular density (VD) values, automatically measured on optical coherence tomography angiography, in healthy Caucasian subjects, demonstrating that age is negatively related to RPC VD values. Results show that RPC VD values in healthy Caucasian subjects decrease with aging. These data may be used to create a reference normative database useful for clinical use.
Authors
- Lenore J. Launer (ORCID: https://orcid.org/0000-0002-3238-7612)
- Andrea Angius (ORCID: https://orcid.org/0000-0003-2596-6461)
- Antonio Pinna (ORCID: https://orcid.org/0000-0003-3052-2662)
- Michele Marongiu (ORCID: https://orcid.org/0000-0002-7289-9815)
- Francesco Cucca (ORCID: https://orcid.org/0000-0002-7414-1995)
- Myriam Gorospe (ORCID: https://orcid.org/0000-0001-5439-3434)
- Florence Coscas (ORCID: https://orcid.org/0000-0002-9888-5040)
- Rita Serra (ORCID: https://orcid.org/0000-0002-6341-1435)
- David Schlessinger (ORCID: https://orcid.org/0000-0002-4622-3352)
- Vincenzo Rallo (ORCID: https://orcid.org/0000-0002-8938-5650)
- Edoardo Fiorillo (ORCID: https://orcid.org/0000-0002-8690-4988)
Institutions
- University of Sassari (IT)
- Centre Ophtalmologique d'Imagerie et de Laser (FR)
- Institute of Genetic and Biomedical Research (IT)
- Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari (IT)
- National Institute on Aging (US)
- National Research Council (IT)
Publication Details
- Journal
- Graefe s Archive for Clinical and Experimental Ophthalmology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1007/s00417-024-06623-6
- Citations
- 3
- Primary Topic
- Cardiovascular Health and Disease Prevention
- Type
- article
- Field-Weighted Citation Impact
- 1.21
Funders
- Foundation for the National Institutes of Health
- Università degli Studi di Sassari
- National Institutes of Health