The Use of Recreational Cannabis Among Breast Reduction Patients: Characteristics, Complications, and Immediate Postoperative Analgesic Needs

<b>Introduction:</b> The characteristics, complications, and postoperative analgesic needs of patients with a recent or active history of recreational cannabis use have not been explored explicitly in plastic surgery. In this study, the characteristics, complications, and postoperative analgesic needs within a population of breast reduction patients who use and do not use recreational cannabis were compared. <b>Methods:</b> A retrospective cohort study was carried out on patients who underwent breast reduction between 2019 and 2023. Demographics, comorbidities, recreational cannabis use, postoperative opioid use, and postoperative complications were collected. Patients with a recent history (<1 month since last cannabis use) or current cannabis use were then compared to patients with no history of cannabis use. <b>Results:</b> In total, 340 patients were included, 88 (26%) patients had a history of cannabis use and 252 (74%) did not. Patients in the cannabis-using group were significantly younger than in the non-cannabis-using group (28 years vs 40 years, <i>P</i> < .01), and significantly more patients in the non-cannabis group had hypertension (20% vs 6% <i>P</i> < .01). More patients in the cannabis-using group had hematomas (5% vs 1%, <i>P</i> = .041) and fewer had t-point breakdown (4% vs 0%, <i>P</i> = .046), but these figures lost statistical significance on multiple logistic regression analysis after controlling for possible confounding factors including demographics and comorbidities (<i>P</i> > .05). There were no significant differences in proportions of opioid use or by doses of opioids, even when converted to oral morphine equivalents (<i>P</i> > .05). <b>Conclusion:</b> The analgesic needs, postoperative pain levels, and complications between cannabis-using and non-cannabis-using cohorts were similar. Counseling on substance use preoperatively should still be encouraged, especially in younger patients seeking reduction mammaplasty.