YELLOW RoUTIne prospective cohort study protocol: insight in the dynamics of bacteria in the elderly bladder
The combination of high ASB prevalence and a reduced ability of frail older adults to express UTI-related S&S may lead to UTI misdiagnosis and inappropriate antibiotic use. To our knowledge, this is the first study to investigate the dynamics and role of bacteriuria in the elderly bladder and their potential protective effect on the development of UTI. The study findings with comprehensive analysis of epidemiological, clinical and molecular data could set the fundamental base for future guidelines and studies, and contribute to improving prevention, diagnosis and treatment of UTI in frail older adults, in addition to contributing to antibiotic stewardship in NHs.
Authors
- Laura W. van Buul (ORCID: https://orcid.org/0000-0001-8753-3464)
- E. Ascelijn Reuland
- Caroline Schneeberger
- Daan W. Notermans (ORCID: https://orcid.org/0000-0002-9494-0989)
- Anja Haenen (ORCID: https://orcid.org/0000-0001-5979-0404)
- Jos W. R. Twisk (ORCID: https://orcid.org/0000-0001-9617-1020)
- Martin Smalbrugge (ORCID: https://orcid.org/0000-0003-0538-4843)
- Suzanne E. Geerlings (ORCID: https://orcid.org/0000-0002-8518-3576)
- Ruochen Wang (ORCID: https://orcid.org/0000-0003-2014-4282)
- Sabine C. de Greeff (ORCID: https://orcid.org/0000-0002-4009-4991)
- K. Halonen
Institutions
- University Medical Center Utrecht (NL)
- National Institute for Public Health and the Environment (NL)
- Amsterdam Neuroscience (NL)
- Tergooi (NL)
- Public Health Service of Amsterdam (NL)
- Amsterdam University Medical Centers (NL)
- Amsterdam University of Applied Sciences (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1186/s12879-024-09727-w
- Citations
- 2
- Primary Topic
- Urinary Tract Infections Management
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- ZonMw