Combining host immune response biomarkers and clinical scores for early prediction of sepsis in infection patients
Patients exhibiting low severity signs of infection but high IL-10 levels showed an elevated probability of developing sepsis. Combining IL-10 with the NEWS score provides a reliable tool for predicting the progression from infection to sepsis at an early stage. Utilizing IL-6 in the emergency room can help identify patients with low NEWS or SIRS scores.
Authors
- Wenqian Deng
- Dongyuan He
- Zhe Xu (ORCID: https://orcid.org/0000-0002-6675-1398)
- Xiaoming Zhou (ORCID: https://orcid.org/0000-0002-6165-9277)
- Jie Weng (ORCID: https://orcid.org/0000-0003-1859-9309)
- Chen Liu (ORCID: https://orcid.org/0000-0002-7797-3869)
- Liang Wang (ORCID: https://orcid.org/0000-0003-4445-8438)
- Zhiyi Wang (ORCID: https://orcid.org/0000-0002-6771-4839)
- Chan Chen (ORCID: https://orcid.org/0000-0001-5823-8247)
- Jingwen Yang
- Hao Wu (ORCID: https://orcid.org/0000-0002-6390-1952)
- Qianhui Cheng (ORCID: https://orcid.org/0000-0002-6350-8608)
- Jiaying Lin (ORCID: https://orcid.org/0009-0008-3431-6106)
- Jiaze Song
- Haijuan Jin
Institutions
- Baylor University (US)
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
- Wenzhou Central Hospital (CN)
- Wenzhou Institute of Technology Testing & Calibration (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1080/07853890.2024.2396569
- Citations
- 6
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.32
Funders
- National Natural Science Foundation of China