Network pharmacology-based mechanism analysis of dauricine on the alleviating Aβ-induced neurotoxicity in Caenorhabditis elegans
Collectively, the mechanism of DAU against AD may be related to the activation of the autophagy-lysosomal protein clearance pathway, which contributes to the decrease of Aβ aggregation and the restoration of protein homeostasis.
Authors
- Ranran Zhang (ORCID: https://orcid.org/0000-0001-5698-1950)
- Qian Zhang (ORCID: https://orcid.org/0000-0002-5862-2190)
- Xiaoliang Xie
- Ju Zhang (ORCID: https://orcid.org/0000-0003-4325-3481)
- Xiaoyan Huang (ORCID: https://orcid.org/0000-0003-3761-4121)
- Dongsheng Jia (ORCID: https://orcid.org/0000-0002-5227-9838)
- Chunling Zhou
Institutions
- Hebei University of Economics and Business (CN)
- Hebei Academy of Agriculture and Forestry Sciences (CN)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1186/s12906-024-04589-w
- Citations
- 2
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.65
Funders
- Natural Science Foundation of Hebei Province
- Horizon 2020 Framework Programme