Influence of selection on the probability of fixation at a locus with multiple alleles
We have analytically exposed the leading way the probability of fixation, at a locus with multiple alleles, is affected by selection. This result may offer important insights into CDCV traits that have extreme phenotypic variance due to numerous, low-penetrance susceptibility alleles.
Authors
- Andrew Overall (ORCID: https://orcid.org/0000-0001-9766-1056)
- David Waxman (ORCID: https://orcid.org/0000-0001-9093-2108)
Institutions
- Fudan University (CN)
- University of Brighton (GB)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1186/s12864-024-10733-0
- Citations
- 1
- Primary Topic
- Evolution and Genetic Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.55