Integrin αVβ6: Autoantigen and Driver of Epithelial Remodeling in Colon and Bile Ducts in Primary Sclerosing Cholangitis and Inflammatory Bowel Disease
Anti-αVβ6 frequently occurs in patients suffering from PSC, especially in PSC-IBD. Anti-αVβ6 levels positively correlate to IBD activity in PSC-IBD, but may also occur in the absence of clinically manifest IBD in PSC.
Authors
- Luis E. Muñoz (ORCID: https://orcid.org/0000-0002-5395-804X)
- Carol Geppert
- Miriam M. Düll (ORCID: https://orcid.org/0000-0001-6335-9158)
- Marcel Vetter (ORCID: https://orcid.org/0000-0002-9619-6647)
- Claudia Günther (ORCID: https://orcid.org/0000-0001-8360-3525)
- Peter Dietrich (ORCID: https://orcid.org/0000-0003-2699-2354)
- Christoph Schramm (ORCID: https://orcid.org/0000-0002-4264-1928)
- Maximilian J. Waldner (ORCID: https://orcid.org/0000-0002-5560-7665)
- André Jefremow (ORCID: https://orcid.org/0000-0002-2041-269X)
- Raja Atreya (ORCID: https://orcid.org/0000-0002-8556-8433)
- Moritz Leppkes (ORCID: https://orcid.org/0000-0003-2311-090X)
- Sebastian Zundler (ORCID: https://orcid.org/0000-0003-0888-2784)
- Aylin Lindemann
- Alexander Scheffold (ORCID: https://orcid.org/0000-0002-0626-343X)
- Sören Weidemann (ORCID: https://orcid.org/0000-0001-7037-3265)
- Kristina Koop (ORCID: https://orcid.org/0000-0002-1672-7234)
- Martin Herrmann (ORCID: https://orcid.org/0000-0002-0258-2484)
- Andreas Emanuel Kremer (ORCID: https://orcid.org/0000-0002-9263-948X)
- Ludwig J. Horst (ORCID: https://orcid.org/0000-0002-0344-6337)
- Xenia Malzer
- Jürgen Siebler
- Markus F. Neurath
- Dominik Roth
Institutions
- Universität Hamburg (DE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Fischer (Germany) (DE)
- Christian-Albrechts-Universität zu Kiel (DE)
- Universitätsklinikum Erlangen (DE)
- University Hospital of Zurich (CH)
- University Medical Center Hamburg-Eppendorf (DE)
- Comprehensive Cancer Center Erlangen (DE)
Publication Details
- Journal
- Journal of Crohn s and Colitis
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1093/ecco-jcc/jjae131
- Citations
- 7
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 2.59
Funders
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung