Autoimmune Sequelae After Delta or Omicron Variant SARS-CoV-2 Infection in a Highly Vaccinated Cohort
This cohort study observed no significantly elevated long-term risk of autoimmune sequelae after SARS-CoV-2 Delta and Omicron BA.1 or BA.2 variant infection, except for a modestly increased risk of inflammatory bowel disease and bullous skin disorders in the hospitalized subgroup during the predominance of the Omicron variant. Booster vaccination appeared to mitigate the risk of long-term autoimmune sequelae.
Authors
- Manjari Lahiri (ORCID: https://orcid.org/0000-0002-3482-6017)
- Ben Ong (ORCID: https://orcid.org/0000-0001-5281-9980)
- Calvin J. Chiew (ORCID: https://orcid.org/0000-0002-8217-7971)
- David Chien Lye (ORCID: https://orcid.org/0000-0003-0324-0205)
- Liang En Wee (ORCID: https://orcid.org/0000-0001-6428-9999)
- Jue Tao Lim (ORCID: https://orcid.org/0000-0002-2245-0331)
- Kelvin Bryan Tan
- An Ting Tay
Institutions
- Ministry of Health (SG)
- National University of Singapore (SG)
- Nanyang Technological University (SG)
- Singapore General Hospital (SG)
- Tan Tock Seng Hospital (SG)
- Duke-NUS Medical School (SG)
- National University Hospital (SG)
- National University Health System (SG)
- National Centre for Infectious Diseases (SG)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.30983
- Citations
- 16
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 6.22
Funders
- Moderna
- Medical Research Council
- National Medical Research Council