Augmented Reality Navigation System (SIRIO) for Neuroprotection in Vertebral Tumoral Ablation
(1) This study evaluates the impact of the CT-guided SIRIO augmented reality navigation system on the procedural efficacy and clinical outcomes of neuroprotection in vertebral thermal ablation (RTA) for primary and metastatic bone tumors. (2) Methods: A retrospective non-randomized analysis of 28 vertebral RTA procedures was conducted, comparing 12 SIRIO-assisted and 16 non-SIRIO-assisted procedures. The primary outcomes included dose-length product (DLP) and epidural dissection time. The secondary outcomes included technical success, complication rates, and pain scores at procedural time (VAS Time 0) and three months post-procedure (VAS Time 1). The statistical analyses included t-tests, Mann-Whitney U tests, and multiple regression. (3) Results: SIRIO-assisted procedures significantly reduced DLP (307.42 mGycm vs. 460.31 mGycm, <i>p</i> = 2.23 × 10<sup>-8</sup>) and procedural epidural dissection time (13.48 min vs. 32.26 min, <i>p</i> = 2.61 × 10<sup>-12</sup>) compared to non-SIRIO-assisted procedures. Multiple regression confirmed these reductions were significant (DLP: β = -162.38, <i>p</i> < 0.001; time: β = -18.25, <i>p</i> < 0.001). Pain scores (VAS Time 1) did not differ significantly between groups, and tumor type did not significantly influence outcomes. (4) Conclusions: The SIRIO system enhances neuroprotection efficacy and safety, reducing radiation dose and procedural time during spine tumoral ablation while maintaining consistent pain management outcomes.
Authors
- Rosario Francesco Grasso (ORCID: https://orcid.org/0000-0001-8660-7070)
- Amalia Bruno (ORCID: https://orcid.org/0000-0002-7459-242X)
- Rebecca Casati
- Bruno Beomonte Zobel (ORCID: https://orcid.org/0000-0001-9227-5535)
- Eliodoro Faiella (ORCID: https://orcid.org/0000-0002-7367-6891)
- Matteo Pileri (ORCID: https://orcid.org/0000-0003-3516-7727)
- Elva Vergantino (ORCID: https://orcid.org/0009-0008-6968-0645)
- Giuseppina Pacella
- Carlo Altomare
Institutions
- Università Campus Bio-Medico (IT)
Publication Details
- Journal
- Current Oncology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3390/curroncol31090376
- Citations
- 5
- Primary Topic
- Medical Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.92