Augmented Reality Navigation System (SIRIO) for Neuroprotection in Vertebral Tumoral Ablation

(1) This study evaluates the impact of the CT-guided SIRIO augmented reality navigation system on the procedural efficacy and clinical outcomes of neuroprotection in vertebral thermal ablation (RTA) for primary and metastatic bone tumors. (2) Methods: A retrospective non-randomized analysis of 28 vertebral RTA procedures was conducted, comparing 12 SIRIO-assisted and 16 non-SIRIO-assisted procedures. The primary outcomes included dose-length product (DLP) and epidural dissection time. The secondary outcomes included technical success, complication rates, and pain scores at procedural time (VAS Time 0) and three months post-procedure (VAS Time 1). The statistical analyses included t-tests, Mann-Whitney U tests, and multiple regression. (3) Results: SIRIO-assisted procedures significantly reduced DLP (307.42 mGycm vs. 460.31 mGycm, <i>p</i> = 2.23 × 10<sup>-8</sup>) and procedural epidural dissection time (13.48 min vs. 32.26 min, <i>p</i> = 2.61 × 10<sup>-12</sup>) compared to non-SIRIO-assisted procedures. Multiple regression confirmed these reductions were significant (DLP: β = -162.38, <i>p</i> < 0.001; time: β = -18.25, <i>p</i> < 0.001). Pain scores (VAS Time 1) did not differ significantly between groups, and tumor type did not significantly influence outcomes. (4) Conclusions: The SIRIO system enhances neuroprotection efficacy and safety, reducing radiation dose and procedural time during spine tumoral ablation while maintaining consistent pain management outcomes.

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Publication Details

Journal
Current Oncology
Published
2024-08-30
DOI
https://doi.org/10.3390/curroncol31090376
Citations
5
Primary Topic
Medical Imaging and Analysis
Type
article
Field-Weighted Citation Impact
0.92
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article

Augmented Reality Navigation System (SIRIO) for Neuroprotection in Vertebral Tumoral Ablation

Rosario Francesco Grasso, Amalia Bruno, Rebecca Casati, Bruno Beomonte Zobel et al.
5 citations
Current Oncology
Medical Imaging and Analysis
0.92
article

Augmented Reality Navigation System (SIRIO) for Neuroprotection in Vertebral Tumoral Ablation

Rosario Francesco Grasso, Amalia Bruno, Rebecca Casati, Bruno Beomonte Zobel, Eliodoro Faiella, Matteo Pileri, Elva Vergantino, Giuseppina Pacella, Carlo Altomare
article en
5 citations

Abstract

(1) This study evaluates the impact of the CT-guided SIRIO augmented reality navigation system on the procedural efficacy and clinical outcomes of neuroprotection in vertebral thermal ablation (RTA) for primary and metastatic bone tumors. (2) Methods: A retrospective non-randomized analysis of 28 vertebral RTA procedures was conducted, comparing 12 SIRIO-assisted and 16 non-SIRIO-assisted procedures. The primary outcomes included dose-length product (DLP) and epidural dissection time. The secondary outcomes included technical success, complication rates, and pain scores at procedural time (VAS Time 0) and three months post-procedure (VAS Time 1). The statistical analyses included t-tests, Mann-Whitney U tests, and multiple regression. (3) Results: SIRIO-assisted procedures significantly reduced DLP (307.42 mGycm vs. 460.31 mGycm, <i>p</i> = 2.23 × 10<sup>-8</sup>) and procedural epidural dissection time (13.48 min vs. 32.26 min, <i>p</i> = 2.61 × 10<sup>-12</sup>) compared to non-SIRIO-assisted procedures. Multiple regression confirmed these reductions were significant (DLP: β = -162.38, <i>p</i> < 0.001; time: β = -18.25, <i>p</i> < 0.001). Pain scores (VAS Time 1) did not differ significantly between groups, and tumor type did not significantly influence outcomes. (4) Conclusions: The SIRIO system enhances neuroprotection efficacy and safety, reducing radiation dose and procedural time during spine tumoral ablation while maintaining consistent pain management outcomes.

Current OncologyVol. 31(9)
Università Campus Bio-Medico (IT)
Good health and well-being
Openalex Percentile: Top 28%
Medical Imaging and Analysis
0.92
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