An Ultra-Low-Voltage Transconductance Stable and Enhanced OTA for ECG Signal Processing

In this paper, a rail-to-rail transconductance stable and enhanced ultra-low-voltage operational transconductance amplifier (OTA) is proposed for electrocardiogram (ECG) signal processing. The variation regularity of the bulk transconductance of pMOS and nMOS transistors and the cancellation mechanism of two types of transconductance variations are revealed. On this basis, a transconductance stabilization and enhancement technique is proposed. By using the "current-reused and transconductance-boosted complementary bulk-driven pseudo-differential pairs" structure, the bulk-driven pseudo-differential pair during the input common-mode range (ICMR) is stabilized and enhanced. The proposed OTA based on this technology is simulated using the TSMC 0.18 μm process in a Cadence environment. The proposed OTA consumes a power below 30 nW at a 0.4 V voltage supply with a DC gain of 54.9 dB and a gain-bandwidth product (GBW) of 14.4 kHz under a 15 pF capacitance load. The OTA has a high small signal figure-of-merit (FoM) of 7410 and excellent common-mode voltage (<i>VCM</i>) stability, with a transconductance variation of about 1.35%. Based on a current-scaling version of the proposed OTA, an OTA-C low-pass filter (LPF) for ECG signal processing with <i>VCM</i> stability is built and simulated. With a -3 dB bandwidth of 250 Hz and a power consumption of 20.23 nW, the filter achieves a FoM of 3.41 × 10^-13, demonstrating good performance.