Indirect effectiveness of a novel SARS-COV-2 vaccine (SCB-2019) in unvaccinated household contacts in the Philippines: A cluster randomised analysis
SCB-2019 demonstrated bias-corrected indirect effectiveness against SARS-CoV-2 infection among HHC, even at a modest coverage level in the household (approximately 25%). Further research into the indirect effects of SARS-CoV-2 vaccines is needed to optimize the impact of limited doses in low and middle-income settings.
Authors
- Birkneh Tilahun Tadesse (ORCID: https://orcid.org/0000-0003-4005-8605)
- Jonathan D. Sugimoto (ORCID: https://orcid.org/0000-0002-1761-328X)
- Florian Marks (ORCID: https://orcid.org/0000-0002-6043-7170)
- May Emmeline B. Montellano
- Josefina Carlos (ORCID: https://orcid.org/0000-0002-2680-4918)
- Hwa Young Kim (ORCID: https://orcid.org/0000-0003-3238-5315)
- Charissa Borja-Tabora (ORCID: https://orcid.org/0000-0002-2056-7763)
- Young Ae You (ORCID: https://orcid.org/0009-0002-4703-2627)
- Asma Binte Aziz (ORCID: https://orcid.org/0000-0003-0203-5744)
- Mari Rose A de Los Reyes
- Lulu Bravo
- Edison Alberto (ORCID: https://orcid.org/0000-0002-0416-2221)
- Milagros Salvani-Bautista
- Sye Lim Hong
- Irene Njau
- Ralf L. Clemens (ORCID: https://orcid.org/0000-0003-4685-4207)
- Camilo C. Roa
Institutions
- International Vaccine Institute (KR)
- Infectious Disease Research Institute (US)
- University of Antananarivo (MG)
- Heidelberg University (DE)
- Asian Hospital and Medical Center (PH)
- University Hospital Heidelberg (DE)
- University of the East Ramon Magsaysay Memorial Medical Center (PH)
- Far Eastern University (PH)
- Tropical Disease Foundation (PH)
- University of the Philippines Manila (PH)
Publication Details
- Journal
- Journal of Infection
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1016/j.jinf.2024.106260
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Coalition for Epidemic Preparedness Innovations