Investigating the therapeutic potential of hesperidin targeting CRISP2 in intervertebral disc degeneration and cancer risk mitigation
Hesperidin, as a potential natural metabolic regulator, not only has therapeutic effects on IDD but may also synergize with estrogen therapy to promote spinal health without increasing cancer risk. This study presents a new clinical approach for IDD treatment and lays the foundation for further drug development and experimental research.
Authors
- Yuqing Jiang (ORCID: https://orcid.org/0000-0002-4202-3038)
- Luming Nong (ORCID: https://orcid.org/0000-0002-4265-3435)
- Tengfei Li (ORCID: https://orcid.org/0000-0001-6142-3865)
- Ruiping Liu (ORCID: https://orcid.org/0000-0003-0366-9853)
- Nanwei Xu (ORCID: https://orcid.org/0000-0001-6927-3312)
- Hui Zhang (ORCID: https://orcid.org/0009-0005-3796-0384)
- Wei Jiang (ORCID: https://orcid.org/0000-0002-9027-4974)
Institutions
- Changzhou No.2 People's Hospital (CN)
- Tianjin Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-29
- DOI
- https://doi.org/10.3389/fphar.2024.1447152
- Citations
- 2
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.85