Single preoperative radiation therapy with delayed surgery for low-risk breast cancer: Oncologic outcome, toxicity and cosmesis of the SPORT-DS phase I trial
Single-fraction preoperative PBI preceding BCS for low-risk breast cancer is feasible, relatively well tolerated and leads to a high level of pR. The 3-month interval after PBI seems to place surgery in a post-radiation inflammatory phase. Further delay between PBI and surgery could improve pR and cosmetic outcome. NCT03917498.
Authors
- Marie‐Christine Guilbert (ORCID: https://orcid.org/0000-0003-0068-0619)
- Danny Lavigne (ORCID: https://orcid.org/0000-0002-4459-9196)
- Mai‐Kim Gervais (ORCID: https://orcid.org/0000-0001-6393-1468)
- David H. Nguyen (ORCID: https://orcid.org/0000-0002-2538-232X)
- Tarek Hijal (ORCID: https://orcid.org/0000-0002-9341-1735)
- David Tiberi (ORCID: https://orcid.org/0000-0001-9875-3323)
- Dima Mahmoud
- Lucas Sidéris (ORCID: https://orcid.org/0000-0002-9326-4392)
- Peter Vavassis
- Michael A. Yassa (ORCID: https://orcid.org/0000-0002-8635-1498)
- Guy Leblanc
- Pierre Dubé
- Michel-Pierre Dufresne
Institutions
- University of Ottawa (CA)
- Ottawa Hospital (CA)
- McGill University Health Centre (CA)
- Hôpital Maisonneuve-Rosemont (CA)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1016/j.radonc.2024.110515
- Citations
- 9
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.57