Survivin inhibition attenuates EGF-induced epithelial mesenchymal transformation of human RPE cells via the EGFR/MAPK pathway
Survivin inhibition attenuates EGF-induced EMT of RPE cells by affecting the EGFR/MAPK signaling pathway. Survivin might be a promising target for preventing PVR.
Authors
- Xiaodong Chen (ORCID: https://orcid.org/0000-0002-4708-0058)
- Huihui Zhang (ORCID: https://orcid.org/0000-0001-8047-5169)
- Sirui Zhou (ORCID: https://orcid.org/0000-0003-4963-0815)
- Yusheng Zhu (ORCID: https://orcid.org/0000-0002-0666-7127)
- Tong Wang (ORCID: https://orcid.org/0000-0002-1828-5935)
- Teng Li (ORCID: https://orcid.org/0009-0004-1047-5752)
- Guowei Wang (ORCID: https://orcid.org/0000-0002-5579-0121)
- Yong Yin
Institutions
- Northwest University (CN)
- Wuhan No.1 Hospital (CN)
- Microbiology Institute of Shaanxi (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1371/journal.pone.0309539
- Citations
- 1
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Northwest University
- Natural Science Foundation of Shaanxi Province