Use of Neuroendoscopy in Combination Treatment of a Three-Year-Old Patient With Primary Disseminated Medulloblastoma: A Case Report

A three-year-four-month-old boy with primary disseminated medulloblastoma M3 stage and secondary occlusive hydrocephalus underwent an endoscopic triventriculocisternostomy (ETVC) and tumor biopsy, followed by ventriculoperitoneal shunt (VPS) placement due to ETVC failure. The treatment regimen, which included intensive induction chemotherapy, proton beam therapy (PBT), and maintenance chemotherapy, led to significant clinical improvement and a complete radiological response. Four years post-treatment, the child remains in remission, illustrating the effectiveness of a multimodal approach in managing complex cases of medulloblastoma in pediatric patients.

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Publication Details

Journal
Cureus
Published
2024-08-30
DOI
https://doi.org/10.7759/cureus.68239
Citations
1
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.44
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Use of Neuroendoscopy in Combination Treatment of a Three-Year-Old Patient With Primary Disseminated Medulloblastoma: A Case Report

Matvey I Livshitz, Manuel de Jesus Encarnacion Ramirez, Gerald Musa, Gervith Reyes Soto et al.
1 citations
Cureus
Glioma Diagnosis and Treatment
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article

Use of Neuroendoscopy in Combination Treatment of a Three-Year-Old Patient With Primary Disseminated Medulloblastoma: A Case Report

Matvey I Livshitz, Manuel de Jesus Encarnacion Ramirez, Gerald Musa, Gervith Reyes Soto, G. E. Chmutin, E. V. Kumirova, Jalolboy A Ashurov, Sirak N Margaryan, S. S. Ozerov
article en
1 citations

Abstract

A three-year-four-month-old boy with primary disseminated medulloblastoma M3 stage and secondary occlusive hydrocephalus underwent an endoscopic triventriculocisternostomy (ETVC) and tumor biopsy, followed by ventriculoperitoneal shunt (VPS) placement due to ETVC failure. The treatment regimen, which included intensive induction chemotherapy, proton beam therapy (PBT), and maintenance chemotherapy, led to significant clinical improvement and a complete radiological response. Four years post-treatment, the child remains in remission, illustrating the effectiveness of a multimodal approach in managing complex cases of medulloblastoma in pediatric patients.

CureusVol. 16(8)
Peoples' Friendship University of Russia (RU), Livingstone Hospital (ZA), Russian Children's Clinical Hospital (RU), National Cancer Institute (UA)
Openalex Percentile: Top 34%
Glioma Diagnosis and Treatment
0.44
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