Use of Neuroendoscopy in Combination Treatment of a Three-Year-Old Patient With Primary Disseminated Medulloblastoma: A Case Report
A three-year-four-month-old boy with primary disseminated medulloblastoma M3 stage and secondary occlusive hydrocephalus underwent an endoscopic triventriculocisternostomy (ETVC) and tumor biopsy, followed by ventriculoperitoneal shunt (VPS) placement due to ETVC failure. The treatment regimen, which included intensive induction chemotherapy, proton beam therapy (PBT), and maintenance chemotherapy, led to significant clinical improvement and a complete radiological response. Four years post-treatment, the child remains in remission, illustrating the effectiveness of a multimodal approach in managing complex cases of medulloblastoma in pediatric patients.
Authors
- Matvey I Livshitz
- Manuel de Jesus Encarnacion Ramirez
- Gerald Musa (ORCID: https://orcid.org/0000-0001-8710-8652)
- Gervith Reyes Soto
- G. E. Chmutin (ORCID: https://orcid.org/0000-0002-3323-508X)
- E. V. Kumirova
- Jalolboy A Ashurov
- Sirak N Margaryan
- S. S. Ozerov
Institutions
- Peoples' Friendship University of Russia (RU)
- Livingstone Hospital (ZA)
- Russian Children's Clinical Hospital (RU)
- National Cancer Institute (UA)
Publication Details
- Journal
- Cureus
- Published
- 2024-08-30
- DOI
- https://doi.org/10.7759/cureus.68239
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.44