Exploring the bidirectional causal association between Sleep Apnea Syndrome and Depression: A Mendelian randomization study involving gut microbiota, serum metabolites, and inflammatory factors
This study provides epidemiological evidence of a bidirectional causal association between SAS and Depression, emphasizing the potential roles of gut microbiota, serum metabolites, and inflammatory factors in the pathogenesis of these disorders. These findings may inform the development of new therapeutic strategies.
Authors
- Yuhao Zeng (ORCID: https://orcid.org/0000-0001-9931-6221)
- Kaiyuan Li (ORCID: https://orcid.org/0000-0001-5037-632X)
- Peng Liu (ORCID: https://orcid.org/0000-0002-3095-0352)
- Jun Ye (ORCID: https://orcid.org/0000-0001-6986-2221)
- Li Zhu
- Miao Liu (ORCID: https://orcid.org/0000-0001-9075-8007)
Institutions
- Nanchang University (CN)
- Dalian Medical University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1016/j.jad.2024.08.153
- Citations
- 6
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.05