A new 1,2,3-triazole-indirubin hybrid suppresses tumor growth and pulmonary metastasis by mitigating the HGF/c-MET axis in hepatocellular carcinoma
CRI9 has been identified as a new inhibitor of the c-MET/PI3K/Akt/mTOR axis in HCC preclinical models.
Authors
- Chakrabhavi Dhananjaya Mohan (ORCID: https://orcid.org/0000-0002-6810-9219)
- Gautam Sethi (ORCID: https://orcid.org/0000-0002-8677-8475)
- Kwang Seok Ahn
- Kachigere B. Harsha
- Kam M. Hui (ORCID: https://orcid.org/0000-0003-1820-1399)
- Amudha Deivasigamani
- Kanchugarakoppal Subbegowda Rangappa (ORCID: https://orcid.org/0000-0003-0572-6305)
- Rajaghatta N. Suresh
- Na Young Kim (ORCID: https://orcid.org/0000-0002-2448-8085)
- Shalini V Gowda
- Darshini Gowda
Institutions
- National University of Singapore (SG)
- University of Mysore (IN)
- Kyung Hee University (KR)
- National University Cancer Institute, Singapore (SG)
- National Cancer Centre Singapore (SG)
- Indian Institute of Toxicology Research (IN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1016/j.jare.2024.08.033
- Citations
- 22
- Primary Topic
- Quinazolinone synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 5.50
Funders
- National Research Foundation
- Ministry of Science, ICT and Future Planning
- National Research Foundation of Korea
- Medical Research Council
- National Medical Research Council