Nonredundant Role of Leishmanolysin-Like (Lmln) Zinc-Metallopeptidase in Retinal Homeostasis
Our work revealed a previously unknown essential role for Lmln in maintaining retinal anatomy and function. Further studies using this new model will be aimed at determining the cellular expression of Lmln and its mechanisms of action within the retina.
Authors
- Sara Ludwig (ORCID: https://orcid.org/0000-0001-5752-6730)
- Bogale Aredo
- Eva Marie Y. Moresco (ORCID: https://orcid.org/0000-0002-2049-7291)
- Bruce Beutler (ORCID: https://orcid.org/0000-0002-3639-246X)
- Rafael L. Ufret-Vincenty (ORCID: https://orcid.org/0000-0001-8022-5119)
- Seher Yüksel (ORCID: https://orcid.org/0000-0003-2373-7809)
- Dogan Can Kirman (ORCID: https://orcid.org/0000-0002-3767-7096)
- Yeshumenesh Zegeye (ORCID: https://orcid.org/0000-0002-3327-4708)
- Emily R. Turpin
- Gizem Ulker-Yilmazer
- Sangita Shrestha
- Yu-Guang He
Institutions
- Southwestern Medical Center (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- American Journal of Ophthalmology
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1016/j.ajo.2024.08.016
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Research to Prevent Blindness
- University of Texas Southwestern Medical Center
- National Institutes of Health
- National Eye Institute