Reagent-Free Intramolecular Hydroamination of Ynone-Tethered Aryl-sulfonamide: Synthesis of Polysubstituted 4-Quinolones
An efficient reagent-free method for the synthesis of polysubstituted 4-quinolone from 2-substituted alkynoyl aryl-sulfonamide was developed. This developed method tolerates various functional groups and gives the corresponding 4-quinolones. We have successfully extended this method to the synthesis of dihydro-4-quinolones from 2-alkenoyl aryl sulfonamide derivatives.
Authors
- Hongjun Jang (ORCID: https://orcid.org/0000-0003-2996-9870)
- Mayavan Viji (ORCID: https://orcid.org/0000-0001-7454-8229)
- Jin‐Ha Hwang (ORCID: https://orcid.org/0000-0002-9581-7413)
- Shanmugam Rajasekar
- Sukgil Song (ORCID: https://orcid.org/0009-0003-9201-3609)
- Jae‐Kyung Jung (ORCID: https://orcid.org/0000-0002-0490-9663)
- Kwanghee Lee
- Hyoungsu Kim (ORCID: https://orcid.org/0000-0002-2774-8727)
- Chanhyun Jung
Institutions
- Chungbuk National University (KR)
- Ajou University (KR)
- Central University of Kashmir (IN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1021/acs.joc.4c00820
- Citations
- 1
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- Chungbuk National University
- National Research Foundation of Korea