CaCl<sub>2</sub>-Citrate Regional Anticoagulation with Continuous Veno-Venous Haemodialysis Leads to Unwanted Chloride Loading Compared to Continuous Veno-Venous Hemofiltration with Systemic Anticoagulation
Compared to CVVH, CVVHD with regional citrate anticoagulation was associated with greater chloride mass transfer to the patient and higher plasma chloride concentrations. This was due to high dialysate chloride concentrations and CaCl2 reinjection. This effect could only be controlled by high net ultrafiltration flow rates.
Authors
- Glenn M. Eastwood (ORCID: https://orcid.org/0000-0001-7700-9933)
- Ian T. Baldwin (ORCID: https://orcid.org/0000-0001-5371-2974)
- Laurent Bitker (ORCID: https://orcid.org/0000-0002-4698-053X)
- Guillaume Deniel (ORCID: https://orcid.org/0000-0002-4006-6114)
- Jean-Christophe Richard (ORCID: https://orcid.org/0000-0003-1503-3035)
- Guillaume David
- Rinaldo Bellomo
- Matthieu Chivot
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Austin Hospital (AU)
Publication Details
- Journal
- Blood Purification
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1159/000541059
- Citations
- 2
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.10