Carbon-Decorated Fe<sub>3</sub>O<sub>4</sub> Nanocomposites as Enhanced Enzyme Mimics for Colorimetric Determination of H<sub>2</sub>O<sub>2</sub> and Glucose
The development of sensitive and accurate glucose biosensors is significant in diabetic patient monitoring. Here, we synthesize carbon-decorated Fe3O4 nanotubes (Fe3O4@C NTs) using a rational designed template method. Through catalytic oxidation of a typical colorimetric reaction, the prepared Fe3O4@C NTs showed significantly better peroxidase-like and oxidase-like performances than other similar Fe3O4-based nanomaterials. Moreover, the optimal pH, temperature, and concentration for Fe3O4@C NTs were 4.0, 60 °C, and 40 μg/mL, respectively. We additionally investigated the steady-state kinetics of Fe3O4@C NTs, and their catalyzed reactions were found to follow the typical Michaelis–Menten model. Based on the peroxidase-like activity of Fe3O4@C NTs, they were employed for label-free, rapid, selective, and highly sensitive colorimetric detection of H2O2 and glucose, demonstrating a potential application for glucose determination.
Authors
- Na Lü (ORCID: https://orcid.org/0000-0001-5771-247X)
- Xianrong Xing
- Caixia Zeng
- Hailong Li (ORCID: https://orcid.org/0000-0002-7608-6598)
- Bin Li (ORCID: https://orcid.org/0000-0002-8509-9833)
- Min Zhang (ORCID: https://orcid.org/0000-0002-5242-0491)
- Heng Liu
Institutions
- Shanghai University of Engineering Science (CN)
- Tianjin University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- ACS Applied Nano Materials
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1021/acsanm.4c03947
- Citations
- 8
- Primary Topic
- Advanced Nanomaterials in Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality
- Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning