Novel insights into vancomycin-loaded calcium sulfate and negative pressure wound therapy in preventing infections in open fractures
VLCS and NPWT demonstrate the ability to alter macrophage behavior toward M2 polarization, which is crucial for infection prevention in open fractures. The synergistic effect of their combined use shows even greater promise in enhancing outcomes in orthopedic trauma care.
Authors
- Rui Xue (ORCID: https://orcid.org/0000-0001-8382-8089)
- Jia Li (ORCID: https://orcid.org/0000-0001-7132-2574)
- Jichao Guo (ORCID: https://orcid.org/0009-0009-4740-1112)
- Bei Jia (ORCID: https://orcid.org/0000-0003-4383-7145)
- Jian‐Ning Liu (ORCID: https://orcid.org/0000-0002-9796-8565)
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1186/s13018-024-04931-5
- Citations
- 2
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- National Outstanding Youth Science Fund Project of National Natural Science Foundation of China