Rearranged During Transfection Rearrangement Detection by Fluorescence In Situ Hybridization Compared With Other Techniques in NSCLC
Overall, both existing literature and our data suggest that <i>RET</i>-FISH testing can be used for rapid screening of <i>RET</i> rearrangements in NSCLC. Nevertheless, using an orthogonal technique such as RNA-seq to confirm <i>RET</i>-FISH-positive cases is essential for ensuring that only patients likely to benefit from <i>RET</i>-target therapy receive the treatment.
Authors
- C. Emprou (ORCID: https://orcid.org/0000-0002-0185-3668)
- Nelly Magnat
- Anne‐Claire Toffart (ORCID: https://orcid.org/0000-0003-4377-0227)
- Julie Mondet (ORCID: https://orcid.org/0000-0002-0765-1100)
- Mailys Mersch
- David Benito
- Diane Giovannini (ORCID: https://orcid.org/0000-0002-0353-1216)
- Anne Mc Leer (ORCID: https://orcid.org/0000-0001-9638-4085)
- Sylvie Lantuéjoul (ORCID: https://orcid.org/0000-0003-4310-6975)
- Nathalie Stürm
Institutions
- Centre Hospitalier Universitaire de Grenoble (FR)
- Centre Léon Bérard (FR)
- Centre de Recherche en Cancérologie de Lyon (FR)
- Translational Innovation in Medicine and Complexity (FR)
- Dubai Medical College (AE)
- Laboratoire Biologie à Grande Échelle (FR)
- Université Grenoble Alpes (FR)
Publication Details
- Journal
- JTO Clinical and Research Reports
- Published
- 2024-08-29
- DOI
- https://doi.org/10.1016/j.jtocrr.2024.100714
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Institut National Du Cancer