Magnitude and predictors of elasticity of demand for morphine are similar in male and female rats
Our findings indicate similar elasticity of demand and predictors of individual differences in demand for morphine in male and female rats, although sex differences were observed in initial rate of acquisition and in some correlations between morphine SA measures. These data are consistent with findings of similar OUD vulnerability in males and females in some human and animal studies.
Authors
- Shirelle X. Liu (ORCID: https://orcid.org/0000-0003-2550-008X)
- Jonathan C. Gewirtz
- John R. Smethells (ORCID: https://orcid.org/0000-0002-8761-5416)
- Peter Muelken
- Andrew C. Harris (ORCID: https://orcid.org/0000-0001-8074-5464)
- Mark LeSage
Institutions
- University of Minnesota (US)
- Hennepin Healthcare Research Institute (US)
- Arizona State University (US)
Publication Details
- Journal
- Frontiers in Behavioral Neuroscience
- Published
- 2024-08-29
- DOI
- https://doi.org/10.3389/fnbeh.2024.1443364
- Citations
- 2
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- University of Minnesota
- National Institutes of Health
- National Institute on Drug Abuse