Genetically predicted HLA-DR+ natural killer cells as potential mediators in the lipid-coronary artery disease/ calcification (CAD/CAC) causal pathway
This study provides preliminary insights into the genetic correlations between lipid metabolism, immune cell dynamics, and CAD susceptibility, highlighting the potential involvement of natural killer cells in the lipid-CAD/CAC causal pathway and suggesting new targets for therapy. Further evidence is necessary to substantiate our findings.
Authors
- Haoyue Zhang (ORCID: https://orcid.org/0000-0002-9412-7584)
- Dingding Qian
- Honghua Ye (ORCID: https://orcid.org/0000-0002-5737-3209)
- Rong Liu (ORCID: https://orcid.org/0000-0001-7477-6520)
Institutions
- Ningbo University (CN)
- Ningbo Medical Center Lihuili Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-08-29
- DOI
- https://doi.org/10.3389/fimmu.2024.1408347
- Citations
- 2
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.48