Celiac disease diagnosis: transglutaminase, duodenal biopsy and genetic tests correlations
In terms of diagnosis tests for CD, transglutaminase levels and age presented an inverse correlation, with the level decreasing as age increased. A moderately positive correlation was found between mean transglutaminase with intestinal atrophy and growth retardation. The genetic test DQ2 was positive for 93% and negative genetic markers (DQ2/DQ8) represented 4.5% of cases studied.
Authors
- Carlos Rodrigo (ORCID: https://orcid.org/0000-0003-1140-2585)
- Laura Martínez‐Martínez (ORCID: https://orcid.org/0000-0003-0126-158X)
- Isabel Badell (ORCID: https://orcid.org/0000-0001-6546-2175)
- Susana Boronat (ORCID: https://orcid.org/0000-0001-7096-5578)
- Katia Regina Pena Schesquini-Roriz
- Gloria Maria Fraga Rodríguez
- Jocelyn Cristina Betancourt Castellanos
Institutions
- Universidade Federal de Rondônia (BR)
- Universitat Autònoma de Barcelona (ES)
- Hospital de Sant Pau (ES)
- Hospital Universitari Germans Trias i Pujol (ES)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2024-08-29
- DOI
- https://doi.org/10.3389/fped.2024.1330511
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00