Sulforaphane regulates cell proliferation and induces apoptotic cell death mediated by ROS-cell cycle arrest in pancreatic cancer cells
Collectively, our data demonstrates that SFN-induced cell death follows the apoptosis pathway, making it a viable target for therapeutic interventions against pancreatic cancer.
Authors
- Bonglee Kim (ORCID: https://orcid.org/0000-0002-8678-156X)
- Yongmin Cho (ORCID: https://orcid.org/0000-0002-8361-9612)
- Abdel Halim Harrath (ORCID: https://orcid.org/0000-0002-2170-1303)
- Tarun Kumar Upadhyay (ORCID: https://orcid.org/0000-0002-2551-9779)
- Jeong Min Oh
- Moon Nyeo Park (ORCID: https://orcid.org/0000-0002-9276-3894)
- Soonki Min (ORCID: https://orcid.org/0000-0002-7341-4138)
- Moonkyoo Kong (ORCID: https://orcid.org/0000-0003-3703-0417)
- Md. Ataur Rahman (ORCID: https://orcid.org/0000-0001-6649-3694)
- Min Ji Choi (ORCID: https://orcid.org/0000-0002-5476-356X)
- Ji-ung Yang
- Seong‐Gyu Ko
- Han Na Kang
Institutions
- University of Michigan (US)
- King Saud University (SA)
- Kyung Hee University (KR)
- Korea Institute of Oriental Medicine (KR)
- Kyung Hee University Medical Center (KR)
- Parul University (IN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-08-29
- DOI
- https://doi.org/10.3389/fonc.2024.1442737
- Citations
- 16
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 3.74
Funders
- National Research Foundation
- King Saud University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea